2025 49ers Schedule

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49ERS SCHEDULE Preseason WK DATE OPPONENT SCOUT/RESULT P1 Mon vs Broncos #29 Lost 6-23 P2 Sat vs Raiders #22 Won 28-6 P3 Sat at Bears #8 Lost 14-20 P4 Thu at Chargers #30 Won 30-6 Regular Season 1 Sun vs Rams #6 Lost 13-20 2 Sun at Eagles #2 Lost 9-10 3 Sun vs Cowboys #9 Lost 42-52 4 Sun at Cardinals #26 Won 22-13 5 Sun vs Colts #23 Lost 24-26 7 Sun at Redskins #28 Match-up 8 Sun vs Buccaneers #20 Match-up 9 Sun vs Giants #17 Match-up 10 Sun at Bears #8 Match-up 11 Sun vs Seahawks #1 Match-up 12 Sun at Titans #32 Match-up 13 Sun vs Cardinals #26 Match-up 14 Sun at Seahawks #1 Match-up 15 Sun at Jaguars #12 Match-up 16 Sat at Rams #6 Match-up 17 Sun vs Texans #3 Match-up